KEGG   Homo sapiens (human): 7318
Entry
7318              CDS       T01001                                 
Symbol
UBA7, D8, UBA1B, UBE1L, UBE2, UBE7
Name
(RefSeq) ubiquitin like modifier activating enzyme 7
  KO
K10698  ubiquitin-activating enzyme E1-like [EC:6.2.1.45]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04120  Ubiquitin mediated proteolysis
hsa05012  Parkinson disease
hsa05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    7318 (UBA7)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    7318 (UBA7)
   05022 Pathways of neurodegeneration - multiple diseases
    7318 (UBA7)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    7318 (UBA7)
Enzymes [BR:hsa01000]
 6. Ligases
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.45  E1 ubiquitin-activating enzyme
     7318 (UBA7)
Ubiquitin system [BR:hsa04121]
 Ubiquitin-activating enzymes (E1)
  UBL-activating enzymes
   7318 (UBA7)
SSDB
Motif
Pfam: ThiF UBA_E1_SCCH E1_FCCH E1_UFD E1_4HB dCache_3
Other DBs
NCBI-GeneID: 7318
NCBI-ProteinID: NP_003326
OMIM: 191325
HGNC: 12471
Ensembl: ENSG00000182179
UniProt: P41226
Structure
Position
3:complement(49805209..49813953)
AA seq 1012 aa
MDALDASKLLDEELYSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLT
LHDPHPTCWSDLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDITEDLLLDFQ
VVVLTAAKLEEQLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPLTAA
IQHISQGSPGILTLRKGANTHYFRDGDLVTFSGIEGMVELNDCDPRSIHVREDGSLEIGD
TTTFSRYLRGGAITEVKRPKTVRHKSLDTALLQPHVVAQSSQEVHHAHCLHQAFCALHKF
QHLHGRPPQPWDPVDAETVVGLARDLEPLKRTEEEPLEEPLDEALVRTVALSSAGVLSPM
VAMLGAVAAQEVLKAISRKFMPLDQWLYFDALDCLPEDGELLPSPEDCALRGSRYDGQIA
VFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQ
FLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRVDGVAAALD
SFQARRYVAARCTHYLKPLLEAGTSGTWGSATVFMPHVTEAYRAPASAAASEDAPYPVCT
VRYFPSTAEHTLQWARHEFEELFRLSAETINHHQQAHTSLADMDEPQTLTLLKPVLGVLR
VRPQNWQDCVAWALGHWKLCFHYGIKQLLRHFPPNKVLEDGTPFWSGPKQCPQPLEFDTN
QDTHLLYVLAAANLYAQMHGLPGSQDWTALRELLKLLPQPDPQQMAPIFASNLELASASA
EFGPEQQKELNKALEVWSVGPPLKPLMFEKDDDSNFHVDFVVAAASLRCQNYGIPPVNRA
QSKRIVGQIIPAIATTTAAVAGLLGLELYKVVSGPRPRSAFRHSYLHLAENYLIRYMPFA
PAIQTFHHLKWTSWDRLKVPAGQPERTLESLLAHLQEQHGLRVRILLHGSALLYAAGWSP
EKQAQHLPLRVTELVQQLTGQAPAPGQRVLVLELSCEGDDEDTAFPPLHYEL
NT seq 3039 nt   +upstreamnt  +downstreamnt
atggatgccctggacgcttcgaagctactggatgaggagctgtattcaagacagctgtat
gtgctgggctcacctgccatgcagaggattcagggagccagggtcctggtgtcaggcctg
cagggcctgggggccgaggtggccaagaacttggttctgatgggtgtgggcagcctcact
ctgcatgatccccaccccacctgctggtccgacctggctgcccagtttctcctctcagag
caggacttggaaaggagcagagccgaggcctctcaagagctcttggctcagctcaacaga
gctgtccaggtcgtcgtgcacacgggtgacatcactgaggacctgctgttggacttccag
gtggtggtgctgactgctgcaaagctggaggagcagctgaaggtgggcaccttgtgtcat
aagcatggagtttgctttctggcggctgacacccggggcctcgtggggcagttgttctgt
gactttggtgaggacttcactgtgcaggaccccacagaggcagaacccctgacagctgcc
atccagcacatctcccagggctcccctggcattctcactctgaggaaaggggccaatacc
cactacttccgtgatggagacttggtgactttctcgggaattgagggaatggttgagctc
aacgactgtgatccccggtctatccacgtgcgggaggatgggtccctggagattggagac
acaacaactttctctcggtacttgcgtggtggggctatcactgaagtcaagagacccaag
actgtgagacataagtccctggacacagccctgctccagccccatgtggtggcccagagc
tcccaggaagttcaccatgcccactgcctgcatcaggccttctgtgcactgcacaagttc
cagcacctccatggccggccaccccagccctgggatcctgttgatgcagagactgtggtg
ggcctggcccgggacctggaaccactgaagcggacagaggaagagccactggaagagcca
ctggatgaggccctagtgcggacagtcgccctaagcagtgcaggtgtcttgagccctatg
gtggccatgctgggtgcagtagctgcccaggaagtgctgaaggcaatctccaggaagttc
atgcctctggaccagtggctttactttgatgccctcgattgtcttccggaagatggggag
ctccttcccagtcctgaggactgtgccctgagaggcagccgctatgatgggcaaattgca
gtgtttggggctggttttcaggagaaactgagacgccagcactacctcctggtgggcgct
ggtgccattggttgtgagctgctcaaagtctttgccctagtgggactgggggccgggaac
agcgggggcttgactgttgttgacatggaccacatagagcgctccaatctcagccgtcag
ttcctcttcaggtcccaggacgttggtagacccaaggcagaggtggctgcagcagctgcc
cggggcctgaacccagacttacaggtgatcccgctcacctacccactggatcccaccaca
gagcacatctatggggataactttttctcccgtgtggatggtgtggctgctgccctggac
agtttccaggcccggcgctatgtggctgctcgttgcacccactatctgaagccactgctg
gaggcaggcacatcgggcacctggggcagtgctacagtattcatgccacatgtgactgag
gcctacagagcccctgcctcagctgcagcttctgaggatgccccctaccctgtctgtacc
gtgcggtacttccctagcacagccgagcacaccctgcagtgggcccggcatgagtttgaa
gaactcttccgactgtctgcagagaccatcaaccaccaccaacaggcacacacttccctg
gcagacatggatgagccacagacactcaccttactgaagccagtgcttggggtcctgaga
gtgcgtccacagaactggcaagactgtgtggcgtgggctcttggccactggaaactctgc
tttcattatggcatcaaacagctgctgaggcacttcccacctaataaagtgcttgaggat
ggaactcccttctggtcaggtcccaaacagtgtccccagcccttggagtttgacaccaac
caagacacacacctcctctacgtactggcagctgccaacctgtatgcccagatgcatggg
ctgcctggctcacaggactggactgcactcagggagctgctgaagctgctgccacagcct
gacccccaacagatggcccccatctttgctagtaatctagagctggcttcggcttctgct
gagtttggccctgagcagcagaaggaactgaacaaagccctggaagtctggagtgtgggc
cctcccctgaagcctctgatgtttgagaaggatgatgacagcaacttccatgtggacttt
gtggtagcggcagctagcctgagatgtcagaactacgggattccaccggtcaaccgtgcc
cagagcaagcgaattgtgggccagattatcccagccattgccaccactacagcagctgtg
gcaggcctgttgggcctggagctgtataaggtggtgagtgggccacggcctcgtagtgcc
tttcgccacagctacctacatctggctgaaaactacctcatccgctatatgccttttgcc
ccagccatccagacgttccatcacctgaagtggacctcttgggaccgtctgaaggtacca
gctgggcagcctgagaggaccctggagtcgctgctggctcatcttcaggagcagcacggg
ttgagggtgaggatcctgctgcacggctcagccctgctctatgcggccggatggtcacct
gaaaagcaggcccagcacctgcccctcagggtgacagaactggttcagcagctgacaggc
caggcacctgctcctgggcagcgggtgttggtgctagagctgagctgtgagggtgacgac
gaggacactgccttcccacctctgcactatgagctgtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (35)   
   KEGG ORTHOLOGY (1)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (15)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (11)   
   RefSeq(nuc) (1)   
   GenBank (5)   
   EMBL (5)   
3D Structure (5)   
   PDB (5)   
Protein domain (6)   
   Pfam (6)   
All databases (69)   

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